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Epigenomic Analysis in Human Disease
The Shen Laboratory focuses on the epigenome and its interaction with the genome in various diseases, with a specific emphasis on female cancers and cross-cancer comparisons.
Recent Publications
Zhou W et al. DNA methylation loss in late-replicating domains is linked to mitotic cell division. Nat Gen
The Cancer Genome Atlas Research Network Group. Comprehensive molecular characterize of papillary renal cell carcinoma. New Eng J Med
Yao L et al. Inferring regulatory element landscapes and transcription factor networks from cancer methylomes. Genome Biol
Cancer Genome Atlas Research Network. Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas. New Eng J Med
Davis CF et al. The somatic genomic landscape of chromophobe renal cell carcinoma. Cancer Cell
Hoadley KA et al. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell
Cancer Genome Atlas Research Network. Comprehensive molecular characterization of gastric adenocarcinoma. Nature
Related Links
Researcher profile: Next generation mentoring
The Cancer Genome Atlas